| Gene Symbol | ANKRD1 |
| Full Name | ANKRD1 — Ankyrin Repeat Domain 1 |
| Aliases | ANKRD1PROTEIN |
| Chromosome | 10q23.31 |
| Protein Type | Gene |
| Function | is a transcriptional coactivator and scaffold protein containing multiple ankyrin repeat domains. |
| Primary Expression | multiple tissues, with highest expression in cardiac muscle, skeletal muscle, and brain |
| Molecular Weight | 36 kDa |
| Amino Acids | 33 aa |
| GeneCards | ANKRD1 |
| Human Protein Atlas | ANKRD1 |
| C-terminal region | Contains nuclear localization signals (NLS) and regulatory sequences |
| YAP1/TAZ signaling | ANKRD1 modulates the Hippo pathway effector YAP1 (Yes-associated protein 1), influencing cell proliferation and survival signals |
| Myocardin interaction | ANKRD1 regulates smooth muscle and cardiac muscle gene expression through interactions with myocardin family transcription factors |
| DNA damage response | ANKRD1 is upregulated in response to DNA damage and oxidative stress, serving as a stress-responsive gene |
| Associated Diseases | Stroke |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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