protein 1,677 words KG: ATAXIN2
Contents

Ataxin-2

🔬 Protein Info
Gene SymbolATAXIN2
Protein FamilyAtaxin-2 family, RNA-binding proteins
Functionis a cytoplasmic RNA-binding protein encoded by the ATXN2 gene that plays critical roles in RNA metabolism, stress granule dynamics, and translational control.
Molecular Weight140 kDa
Amino Acids1313 aa
UniProt IDQ99700
GeneCardsATAXIN2
Human Protein AtlasATAXIN2
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (6)

Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
APOE-Dependent Autophagy Restoration
Score: 0.89
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
mitochondrial-dysfunction-neurodegeneration-comparison
disease · Pages share 4 hypotheses
Familial vs Sporadic Neurodegeneration Comparison
disease · Pages share 4 hypotheses
UPenn Observational Research Repository (NCT04715399)
clinical · Pages share 4 hypotheses
TARDBP Mutations in Amyotrophic Lateral Sclerosis
disease · Pages share 4 hypotheses

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