protein 1,194 words KG: BAFFR 2026-03-30
kind:proteinsection:proteinsstate:published
Contents

BAFFR (B Cell Activating Factor Receptor) Protein

🔬 Protein Info
Gene SymbolTNFRSF13C
Full NameTNF Receptor Superfamily Member 13C
Chromosome22q12.1
Protein FamilyTNF receptor superfamily
Protein TypeType I transmembrane receptor
Functionis a critical member of the TNF receptor superfamily that plays an essential and non-redundant role in B cell survival, maturation, and homeostasis.
Molecular Weight~19.2 kDa
Exons5
PathwaysWnt
UniProt IDQ9Y239
NCBI Gene ID115650
Ensembl IDENSG00000159958
OMIM606269
GeneCardsTNFRSF13C
Human Protein AtlasTNFRSF13C
Associated DiseasesAtaxia, Neurodegeneration, Spinocerebellar Ataxia, disease
InteractionsHCRTR1, CHRM4, MYO7A, ADRA2B, GRM2, CRH
KG Connections66 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in