protein 2,464 words KG: CATHEPSINK 2026-03-29
section:proteinskind:proteintopic:alzheimerstopic:parkinsons
Contents

Cathepsin K

🔬 Protein Info
Gene SymbolCTSK
Full NameCathepsin K
Chromosome1q21.3
Protein FamilyPapain family cysteine proteases
Protein TypeProtease
Functionis a gene encoding a member of the papain family of cysteine proteases with remarkable collagenolytic activity.
Primary Expressionvarious tissues including the brain, where it participates in extracellular matrix remodeling, protein aggregate clearance, and neuroinflammatory proc
Subcellular LocalizationLysosomes, bone resorption lacunae
Molecular Weight24.9 kDa
Amino Acids329 aa
UniProt IDP43235
NCBI Gene ID1523
Ensembl IDENSG00000143351
OMIM601105
GeneCardsCTSK
Human Protein AtlasCTSK
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph