protein 2,806 words KG: GRIN2D
Contents

GRIN2D Protein

🔬 Protein Info
Gene SymbolGRIN2D
Full NameGlutamate Ionotropic Receptor NMDA Type Subunit 2D
Chromosome19q13.12
FunctionGluN2D-containing NMDA receptors have unique functional properties
Primary Expressionvarious brainstem nuclei controlling autonomic functions - Cortex: Transient high expression during development, declining in adulthood - Cerebe
Subcellular Localization</strong></td><td>Postsynaptic density, extrasynaptic membranes</td></tr>
Molecular Weight175 kDa
Amino Acids356 aa
Gene TypeProtein coding
UniProt IDQ9UQF8
NCBI Gene ID2904
Ensembl IDENSG00000182308
GeneCardsGRIN2D
Human Protein AtlasGRIN2D
Amino-terminal domain (ATD)Regulates receptor assembly and modulates channel gating. The ATD of GluN2D influences receptor deactivation kinetics and sensitivity to allosteric modulators.
Associated Diseasesneurodegeneration
KG Connections5 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph