Contents

GRIP2 Protein - Glutamate Receptor Interacting Protein 2

🔬 Protein Info

Gene Symbol	GRIP2
Full Name	Glutamate Receptor Interacting Protein 2
Aliases	Page for GRIP2, Page for GRIP2 Protein
Chromosome	3p24.3
Protein Type	Protein
Function	is a neuronal scaffolding protein that plays essential roles in synaptic function, plasticity, and trafficking of ionotropic glutamate receptors.
Primary Expression	the brain, with high levels in the hippocampus, cortex, and cerebellum—regions critical for learning, memory, and motor coord
Molecular Weight	112.8 kDa
Amino Acids	1112 aa
UniProt ID	Search UniProt
GeneCards	GRIP2
Human Protein Atlas	GRIP2
PDZ domains 1-2	Bind to the C-terminal PDZ-binding motifs of AMPA receptor subunits
PDZ domains 3-5	Interact with other scaffolding proteins (GRIP1, PICK1)
PDZ domains 6-7	Connect to additional binding partners and signaling proteins
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

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