| Gene Symbol | HTR6PROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the brain, particularly in areas important for cognition and emotion (olfactory tubercle, nucleus accumbens, striatum, hippocampus) |
| Subcellular Localization | Unlike most 5-HT receptors, HTR6 exclusively couples to Gs proteins, making it u |
| Molecular Weight | 50 kDa |
| GeneCards | HTR6PROTEIN |
| Human Protein Atlas | HTR6PROTEIN |
| Differential splicing | Generates isoforms with distinct pharmacological profiles |
| Cysteine residues | In extracellular loops for disulfide bond formation |
| Palmitoylation sites | For membrane localization |
| Cognitive enhancement | Hippocampal and cortical signaling improves learning and memory |
| Mood regulation | Modulates serotonergic signaling in limbic regions |
| Food intake | Hypothalamic HTR6 regulates appetite |
| Neuroprotection | May have trophic effects on neurons |
| Associated Diseases | Bipolar |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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