protein 645 words KG: KDM3BPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

KDM3B Protein (Lysine Specific Demethylase 3B (JHDM2B))

🔬 Protein Info
Gene SymbolKDM3B
Full NameLysine Specific Demethylase 3B
AliasesPage for KDM3B, Lysine Specific Demethylase 3B (JHDM2B
Chromosome5q31.1
Protein FamilyJHDM3/KDM3 family (Jumonji C domain demethylase)
Functionis a Jumonji C (JmjC) domain-containing histone demethylase that catalyzes the removal of methyl groups from histone lysine residues.
Primary Expressionmultiple brain regions:
UniProt IDQ7Z6W4
NCBI Gene ID55693
Ensembl IDENSG00000106479
OMIM607395
GeneCardsKDM3B
Human Protein AtlasKDM3B
Associated DiseasesChildhood Interstitial Lung Disease, Litter Size, Live Lamb Number, Live Lamb Rate, Pregnancy Duration, Pulmonary Arterial Hypertension
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

Related Experiments (2)

Epigenetic Dysregulation in Huntington's Disease — Therapeut
validation · proposed · Score: 0.40
Microglial Contributions to Huntington's Disease Pathogenesi
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in