PULMONARY ARTERIAL HYPERTENSION

Understanding Entity Pages

This page aggregates everything SciDEX knows about PULMONARY ARTERIAL HYPERTENSION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    PULMONARY_ARTERIAL_HYPERTENSIO["PULMONARY ARTERIAL HYPERTENSION"]
    PULMONARY_ARTERIAL_HYPERTENSIO -->|"causes"| Endothelial_Cell_Dysfunction["Endothelial Cell Dysfunction"]
    PULMONARY_ARTERIAL_HYPERTENSIO -->|"causes"| Pulmonary_Arterial_Endothelial["Pulmonary Arterial Endothelial Cell Dysfunction"]
    PULMONARY_ARTERIAL_HYPERTENSIO -->|"induces"| APOPTOSIS["APOPTOSIS"]
    Pulmonary_Vascular_Resistance_["Pulmonary Vascular Resistance Increase"] -->|"contributes to"| PULMONARY_ARTERIAL_HYPERTENSIO
    Monocyte_Tissue_Infiltration["Monocyte Tissue Infiltration"] -->|"contributes to"| PULMONARY_ARTERIAL_HYPERTENSIO
    LDLR_FAMILY_RECEPTORS["LDLR FAMILY RECEPTORS"] -->|"involved_in"| PULMONARY_ARTERIAL_HYPERTENSIO
    LDLR["LDLR"] -->|"involved_in"| PULMONARY_ARTERIAL_HYPERTENSIO
    LRP2["LRP2"] -->|"involved_in"| PULMONARY_ARTERIAL_HYPERTENSIO
    KCNK3["KCNK3"] -->|"causes"| PULMONARY_ARTERIAL_HYPERTENSIO
    LRP1["LRP1"] -->|"involved_in"| PULMONARY_ARTERIAL_HYPERTENSIO
    PDGF["PDGF"] -->|"involved_in"| PULMONARY_ARTERIAL_HYPERTENSIO