| Gene Symbol | MATR3 |
| Full Name | MATRIN3 |
| Aliases | MATRIN3PROTEIN |
| Protein Family | Matrin-3 family, RNA-binding proteins |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Nuclear matrix, speckles |
| Molecular Weight | 125 kDa |
| Amino Acids | 847 aa |
| Pathways | Autophagy, Proteasome, Ubiquitin-Proteasome |
| UniProt ID | P43243 |
| GeneCards | MATR3 |
| Human Protein Atlas | MATR3 |
| RNA Stability | MATRIN3 can bind to specific mRNAs and regulate their stability, potentially protecting transcripts from degradation or facilitating their turnover. |
| Transcriptional Regulation | Through interactions with transcription factors and chromatin-modifying enzymes, MATRIN3 can influence gene expression at multiple levels[@coeffet2018]. |
| Associated Diseases | ALS |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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