protein 1,166 words KG: MBD4PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

MBD4 Protein - Methyl-CpG Binding Domain Protein 4

🔬 Protein Info
Gene SymbolMBD4
Full NameMBD4 - Methyl-CpG Binding Domain Protein 4
AliasesPage for MBD4 Gene, Page for MBD4 Protein
Chromosome18q21.2.
Protein TypeGene
Functionis a DNA repair enzyme encoded by the MBD4 gene located on chromosome 18q21.
Primary Expressionmost human tissues with particular significance in: - Brain (neurons, astrocytes, microglia) - Hematopoietic system - Gastroin
Subcellular Localizationmethylated DNA:
Amino Acids606 aa
Exons16
GeneCardsMBD4
Human Protein AtlasMBD4
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (10)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
PARP1 Inhibition Therapy
Score: 0.58
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in