protein 810 words KG: MBD5PROTEIN
Contents

MBD5 Protein - Methyl-CpG Binding Domain Protein 5

🔬 Protein Info
Gene SymbolMBD5
Full NameMethyl-CpG Binding Domain Protein 5
AliasesPage for MBD5 Gene, Page for MBD5 Protein
Chromosome2q23.1.
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe brain and is essential for normal neuronal development and function
Molecular Weight225 kDa
Amino Acids80 aa
UniProt ID[Q9P523](https://www.uniprot.org/uniprot/Q9P523)
Ensembl IDENSG00000180573
GeneCardsMBD5
Human Protein AtlasMBD5
Chromatin remodeling recruitmentRecruits histone modifiers and chromatin remodelers
Gene-specific targetingRegulates specific gene networks important for neuronal function
Cortical developmentRegulates neuronal proliferation and differentiation
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (10)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.