| Gene Symbol | OSMR |
| Full Name | Oncostatin M Receptor |
| Chromosome | 5p13.1 |
| Protein Type | Receptor |
| Function | encodes a type I cytokine receptor that mediates signaling from IL-6 family cytokines, primarily Oncostatin M (OSM) and Leukemia Inhibitory Factor (LIF) [@breedlove2020]. |
| Primary Expression | the CNS, with particularly high levels on reactive astrocytes surrounding sites of pathology |
| Molecular Weight | 110 kDa |
| Amino Acids | 979 aa |
| Exons | 12 |
| Pathways | MAPK, PI3K, PI3K pathway |
| UniProt ID | Q08357 |
| NCBI Gene ID | 9184 |
| Ensembl ID | ENSG00000120708 |
| OMIM | 601095 |
| GeneCards | OSMR |
| Human Protein Atlas | OSMR |
| Associated Diseases | Als, Alzheimer, Cancer Cachexia, Dementia, Inflammation, Ms |
| Interactions | DRP1, Rb, AUTOPHAGY, Caspase, Actin, Ras |
| KG Connections | 58 knowledge graph edges |
| Databases | GeneCardsHPASTRING |