protein 985 words KG: P19589 2026-03-27
kind:proteinsection:proteinsstate:published
Contents

PKR Protein (Protein Kinase R)

🔬 Protein Info
Gene SymbolP19589
Protein FamilySerine/Threonine Kinase (PKR family)
Protein TypeKinase
Functionis a serine/threonine protein kinase that plays a central role in the cellular stress response, particularly in antiviral defense and translational control[@b愛德华茲2020].
Primary ExpressionUbiquitous, high in brain
Subcellular LocalizationCytoplasm, nucleus
Molecular Weight~62 kDa
UniProt IDP19589
GeneCardsP19589
Human Protein AtlasP19589
GeneEIF2AK2
PDB Structures2E7O, 3UI8, 5Y36
Associated Diseasesneurodegeneration
KG Connections2 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph