| Gene Symbol | PDE1A |
| Full Name | Phosphodiesterase 1A |
| Aliases | PDE1APROTEIN |
| Function | PDE1A catalyzes the hydrolysis of |
| Subcellular Localization | ** | Cytosol, membrane | |
| UniProt ID | O00408 |
| Ensembl ID | ENSG00000115252 |
| GeneCards | PDE1A |
| Human Protein Atlas | PDE1A |
| N-terminal regulatory domain | Contains two calmodulin-binding motifs |
| Catalytic domain | C-terminal hydrolase domain with zinc binding motif |
| Dimerization interface | Forms homodimers |
| cAMP levels | Controls cAMP signaling duration and amplitude |
| cGMP levels | Modulates cGMP-mediated signaling |
| Calcium signaling | Integrates Ca²⁺ and cAMP pathways |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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