| Gene Symbol | PON2 |
| Full Name | Paraoxonase 2 |
| Chromosome | 7q21.3 |
| Protein Family | Paraoxonase family |
| Function | 1. ROS reduction: PON2 inhibits mitochondrial ROS production by modulating Complex I activity |
| Primary Expression | the liver and secreted into the plasma, PON2 exhibits a broader tissue distribution with particularly high expression in the brain, lung, and heart |
| Subcellular Localization | Endoplasmic Reticulum, Mitochondria, Cytoplasm |
| Molecular Weight | ~39 kDa |
| Amino Acids | 354 aa |
| UniProt ID | Q15165 |
| Ensembl ID | ENSG00000105855 |
| GeneCards | PON2 |
| Human Protein Atlas | PON2 |
| Protein Name | Paraoxonase 2 |
| Enzyme Activity | Lactonase, Organophosphatase, Antioxidant |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |