protein 1,261 words KG: RARBPROTEIN 2026-03-29
kind:proteinsection:proteinstopic:alzheimerstopic:parkinsons
Contents

Retinoic Acid Receptor Beta

🔬 Protein Info
Gene SymbolRARBPROTEIN
Chromosome3p24
Protein TypeTranscription Factor
Functionis a ligand-activated transcription factor belonging to the nuclear receptor superfamily, mediating the genomic effects of all-trans retinoic acid (ATRA) and related retinoids[@maden2001].
Primary Expressionhippocampus, cortex, and substantia nigra
Subcellular Localizationsignal (NLS), and allows conformational flexibility important for cofactor recru
Molecular Weight50 kDa
GeneCardsRARBPROTEIN
Human Protein AtlasRARBPROTEIN
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.56
HDAC3-Selective Inhibition for Clock Reset
Score: 0.46
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.65

Related Analyses (11)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in