protein 563 words KG: XRCC6PROTEIN
Contents

Ku70 Protein

🔬 Protein Info
Gene SymbolXRCC6PROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization** | Nucleus |
Molecular Weight70 kDa
GeneCardsXRCC6PROTEIN
Human Protein AtlasXRCC6PROTEIN
Domain architectureKu Protein Family domain organization
Key motifsDNA-binding domains, catalytic residues
Post-translational modificationsPhosphorylation, ubiquitination, SUMOylation
DNA repairEssential for maintaining genomic integrity
Cell survivalCoordinates DNA damage response with cell survival
Neuronal functionRequired for long-term neuronal survival
Genome stabilityPrevents accumulation of mutations
NeurodegenerationImpaired DNA repair leads to neuronal dysfunction
AgingDNA repair decline is a hallmark of brain aging
Associated Diseasesneurodegeneration
InteractionsApp, HERC5, RNA, UBIQUITIN
KG Connections6 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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