gene 889 words KG: SEC61A1 2026-03-24
kind:genesection:genesstate:published
Contents

SEC61A1 - Sec61 Translocon Alpha 1

🧬 Gene Info
Gene SymbolSEC61A1
Full NameSec61 Translocon Alpha 1
AliasesPage for SEC61A1, Page for SEC61A1 Protein
Chromosome3q21.3
FunctionCo-translational Translocation: As the ribosome synthesizes a nascent polypeptide with an ER signal sequence, the Sec61 channel allows the growing chain to pass directly into the ER lumen [2]
Primary ExpressionCerebral cortex, Hippocampus, Basal ganglia, Spinal cord
Molecular Weight52 kDa
UniProt IDP61019
NCBI Gene ID29927
Ensembl IDENSG00000058262
OMIM609163
GeneCardsSEC61A1
Human Protein AtlasSEC61A1
Symbol [@gorlich2000] SEC61A1 [@rabi2020] [@hegde2009] Full NameSEC61 Translocon Alpha 1 Subunit
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis
DatabasesGeneCardsHPASTRING

Knowledge Graph

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