therapeutic 804 words KG: ent-gene-9f063e98 2026-03-22
kind:therapeuticsection:therapeuticsstate:published
Contents

LRRK2 Inhibitors for Parkinson's Disease

🔬 Protein Info
Gene Symbolent-gene-9f063e98
CategoryDisease-Modifying Therapy
TargetLRRK2 (Leucine-Rich Repeat Kinase 2)
Development StagePhase I-II Clinical Trials
RouteOral
DrugCompany
G007-LKGenentech
LRRK2-IN-1Various
MutationDomain
G2019SKinase
R1441C/G/HROC
Y1699CCOR
I2020TKinase
CompanyDrug
Denali/DietsmannDNL151/Lunagrelpar
BiogenBIIB122
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Analyses (15)

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Related Experiments (30)

AAV Serotype Comparison for LRRK2 Knockdown in PD Gene Thera
validation · proposed · Score: 0.40
AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
AAV Serotype Comparison for LRRK2 Knockdown in PD
validation · proposed · Score: 0.40
Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio
clinical · proposed · Score: 0.40
Computational Modeling of Alpha-Synuclein Propagation in PD
validation · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-9f063e98 data_in benchmark_ot_ad_answer_key:LRRK2
benchmark_ot_ad_answer_key:LRRK2 data_in ent-gene-9f063e98