therapeutic 1,907 words KG: ent-gene-bd555192
Contents

NURR1 Agonist Therapy for Parkinson's Disease

🔬 Protein Info
Gene Symbolent-gene-bd555192
Chromosome2q22
FunctionThese targets explain why NURR1 activation is crucial for maintaining dopaminergic neuron identity and function [@nurr2020]
Substantia nigra pars compacta (SNc)The primary location of dopaminergic neurons that degenerate in PD
Ventral tegmental area (VTA)Contains dopaminergic neurons projecting to cortical and limbic regions
StriatumReceives dopaminergic innervation from the SNc
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (43)

PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor
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Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
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Vagal Afferent Microbial Signal Modulation
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Vocal Cord Neuroplasticity Stimulation
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Related Analyses (30)

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Related Experiments (30)

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clinical · proposed · Score: 0.40
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Key Papers (1)

Assessment of the Spatial Distribution of Moisture Content in Granular
Sensors (Basel, Switzerland) 2024

See Also (6)

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nct05508789
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Knowledge Graph (2 edges)

ent-gene-bd555192 data_in benchmark_ot_ad_answer_key:NURR1
benchmark_ot_ad_answer_key:NURR1 data_in ent-gene-bd555192

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