Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,491 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,491)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 283 pages matching "RET"

🔬 Beta-Secretase (BACE1) ProteinKG

protein · 3,982 words · 53 hyp24 ana5 exp

⚙️ Retromer Dysfunction in Corticobasal SyndromeKG

mechanism · 3,576 words · 16 hyp40 ana12 exp

⚙️ Endoplasmic Reticulum Stress Comparison Across Neurodegenerative DiseasesKG

mechanism · 3,363 words · 15 hyp41 ana2 exp

🔬 Gamma-Secretase Complex (γ-Secretase)KG

protein · 3,346 words · 13 hyp6 ana2 exp

⚙️ VPS35 Retromer Dysfunction Parkinson's Disease Causal ChainKG

mechanism · 3,215 words · 5 hyp43 ana63 exp

⚙️ endoplasmic-reticulum-stressKG

mechanism · 3,156 words · 18 hyp35 ana

⚙️ Retinal Biomarkers in NeurodegenerationKG

mechanism · 3,115 words · 278 hyp57 ana55 exp

🧬 RXRG — Retinoid X Receptor GammaKG

gene · 3,085 words · 33 hyp8 ana5 exp

🏥 X-Linked Intellectual DisabilityKG

disease · 3,062 words · 7 hyp6 ana4 exp

⚙️ Retromer Dysfunction in NeurodegenerationKG

mechanism · 3,047 words · 282 hyp54 ana56 exp

💡 VPS35 Retromer Stabilizer for Lysosomal RescueKG

idea · 2,957 words · 16 hyp9 ana4 exp

⚙️ Orexin/Hypocretin Signaling Pathway in NeurodegenerationKG

mechanism · 2,948 words · 289 hyp56 ana54 exp

⚙️ VPS35/Retromer Pathway in Parkinson's DiseaseKG

mechanism · 2,946 words · 21 hyp47 ana63 exp

⚙️ Pretangle in NeurodegenerationKG

mechanism · 2,929 words · 286 hyp57 ana66 exp

⚙️ Retrograde Axonal Transport Dysfunction in NeurodegenerationKG

mechanism · 2,905 words · 285 hyp54 ana58 exp

🧬 RETREG3 (Reticulophagy Regulator 3)KG

gene · 2,881 words · 4 hyp5 ana

💊 Retromer Stabilizers for NeurodegenerationKG

therapeutic · 2,860 words · 279 hyp50 ana54 exp

📊 p-Tau Biomarker in Immunoglobulin Light Chain and Transthyretin AmyloidosisKG

biomarker · 2,836 words · 16 hyp5 ana15 exp

ER-Golgi Secretory Pathway Dysfunction Hypothesis in Parkinson's DiseaseKG

hypothesis · 2,790 words · 6 hyp27 ana61 exp

🔬 Reticulotegmental Nucleus (RtTg)KG

cell · 2,676 words · 4 hyp5 ana

🧪 AMDX-2011P Retinal Amyloid Tracer in Alzheimer's DiseaseKG

clinical · 2,654 words · 69 hyp27 ana61 exp

🔬 Lateral Hypothalamus Orexin/Hypocretin NeuronsKG

cell · 2,641 words · 9 hyp14 ana1 exp

Retinal Rod Photoreceptors NeurodegenerationKG

cell_type · 2,604 words · 281 hyp53 ana54 exp

🔬 ER Stress NeuronsKG

cell · 2,555 words · 11 hyp14 ana3 exp

🔬 Tyramine/Hypocretin NeuronsKG

cell · 2,472 words · 6 hyp13 ana1 exp

retinal-amacrine-cells-parkinsons-diseaseKG

cell_type · 2,333 words · 203 hyp18 ana1 exp

🔬 Orexin/Hypocretin NeuronsKG

cell · 2,248 words · 12 hyp14 ana3 exp

🔬 Substantia Nigra Pars Reticulata GABAergic Output NeuronsKG

cell · 2,229 words · 6 hyp12 ana1 exp

⚙️ Retinal Degeneration Pathway in NeurodegenerationKG

mechanism · 2,170 words · 291 hyp58 ana54 exp

⚙️ Human Endogenous Retroviruses in Neurodegenerative DiseasesKG

mechanism · 2,162 words · 140 hyp62 ana2 exp

🔬 GUCY2F (Retinal Guanylate Cyclase 2F)KG

protein · 2,108 words · 5 hyp8 ana

🏥 Hereditary Transthyretin Amyloidosis (hATTR)KG

disease · 2,042 words · 3 hyp4 ana14 exp

💊 VPS35/Retromer Stabilizers for Parkinson's DiseaseKG

therapeutic · 2,015 words · 9 hyp17 ana63 exp

🔬 Parvicellular Reticular NucleusKG

cell · 1,977 words · 4 hyp5 ana

⚙️ Alpha-Synuclein Exosomal SecretionKG

mechanism · 1,966 words · 8 hyp34 ana4 exp

🔬 Thalamic Reticular Nucleus in EpilepsyKG

cell · 1,964 words · 6 hyp6 ana1 exp

🔬 Reticularis Pontis Oralis NeuronsKG

cell · 1,961 words · 9 hyp10 ana10 exp

retromer-endosomal-sorting-parkinsonsKG

general · 1,948 words · 5 hyp2 ana7 exp

🔬 Olivary Pretectal NucleusKG

cell · 1,916 words · 4 hyp5 ana1 exp

💊 Secretoneurin Neuropeptide TherapyKG

therapeutic · 1,907 words · 50 hyp22 ana13 exp

🔬 Substantia Nigra Pars Reticulata GABA Output NeuronsKG

cell · 1,832 words · 5 hyp11 ana3 exp

Retromer-Endosomal Sorting Dysfunction Hypothesis in Parkinson's DiseaseKG

hypothesis · 1,808 words · 2 hyp21 ana60 exp

🔬 Photoreceptors in Light DetectionKG

cell · 1,806 words · 6 hyp7 ana1 exp

⚙️ Retrograde Transport and Endosomal Pathway DysfunctionKG

mechanism · 1,795 words · 42 hyp42 ana6 exp

💊 Natriuretic Peptide Receptor Modulators for NeurodegenerationKG

therapeutic · 1,791 words · 281 hyp54 ana66 exp

🔬 Olivary Pretectal Nucleus NeuronsKG

cell · 1,759 words · 5 hyp11 ana1 exp

🔬 Retromammillary Nucleus NeuronsKG

cell · 1,753 words · 5 hyp11 ana1 exp

Retinal Imaging in NeurodegenerationKG

diagnostic · 1,749 words · 278 hyp40 ana55 exp

🏥 Rett SyndromeKG

disease · 1,730 words · 16 hyp7 ana3 exp

💡 VPS35 Retromer Pharmacological ChaperoneKG

idea · 1,722 words · 3 hyp2 ana2 exp

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