TREM2-ASM Crosstalk in Microglial Lysosomal Senescence

h-var-18aae53fe9

## Mechanistic Overview TREM2-ASM Crosstalk in Microglial Lysosomal Senescence starts from the claim that modulating SMPD1 within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "**Molecular Mechanism and Rationale** The TREM2-ASM crosstalk hypothesis centers on the intersection of microglial immunoreceptor signaling and sphingolipi