📄
STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle.
active
paper
Created: 2026-04-17T10:19:38
By: etl-v1-backfill
Quality:
50%
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ID: 737592f9-312c-49b8-84ba-e3db425ba162
📄 Paper Details
STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle.
["Joseph M Hoolachan", "Rekha Balakrishnan", "Erika M McCown", "Karla E Merz", "Chunxue Zhou", "Elizabeth Bloom-Saldana", "Patrick T Fueger", "Angelica Hamilton", "Tali Kiperman", "Ke Ma", "Eunjin Oh"
Abstract
BACKGROUND: Mitochondrial homeostasis is vital for optimal skeletal muscle integrity. Mitochondrial quality control (MQC) mechanisms that are essential for maintaining proper functions of mitochondria include mitochondrial biogenesis, dynamics and mitophagy. Previously, Syntaxin 4 (STX4), traditionally considered a cell surface protein known for glucose uptake in skeletal muscle, was also identified at the outer mitochondrial membrane. STX4 enrichment was sufficient to reverse Type 2 diabetes-as...
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | papers |
| _schema_version | 1 |
📊 Evidence Profile
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