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Proximity labeling approach combined with proteomics identified subcellular molecular architecture of spheroids in human postmortem brains, revealing abnormalities in protein turnover, cytoskeleton dynamics, and lipid transport.

active
experiment Created: 2026-04-27T23:17:19 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-0248e0454158
🧫 Experiment Protocol ComputationalAlzheimer's diseaseMTORhumanextracted
Proximity labeling approach for spheroid proteome analysis in human postmortem brains
PRIMARY OUTCOME
Proximity labeling approach combined with proteomics identified subcellular molecular architecture of spheroids in human postmortem brains, revealing abnormalities in protein turnover, cytoskeleton dynamics, and lipid transport.
Source: pmid_40065072
🧫 Experiment Extras
PATHWAY
PI3K/AKT/mTOR pathway
MARKET PRICE
$0.50
STATUS
extracted
Related Target
MTORcomposite 0.419
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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