🧫
In midlife, lower Aβ42:Aβ40 ratio was associated with increased risk of incident all-cause dementia over 6-7 years of follow-up (HR 1.11 per SD lower).
active
experiment
Created: 2026-04-27T23:21:59
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-73b706f96112
🧫 Experiment Protocol
ClinicalAlzheimer's diseasehumanextracted
Plasma biomarkers measured using Quanterix Simoa platform from stored specimens; dementia ascertained by neuropsychological assessment, participant contact, and medical record surveillance
PRIMARY OUTCOME
In midlife, lower Aβ42:Aβ40 ratio was associated with increased risk of incident all-cause dementia over 6-7 years of follow-up (HR 1.11 per SD lower).
LINKED HYPOTHESES
Source: pmid_39068543
🧫 Experiment Extras
PATHWAY
amyloid-beta metabolism
MARKET PRICE
$0.50
STATUS
extracted
Prediction Markets (1 direct, 0 via hypothesis — 1 total)
In midlife, lower Aβ42:Aβ40 ratio was associated with increased risk of incident all-causeYES 38% · Liq $100 · cancelled▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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