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Human iPSC-derived AD model with optical electrophysiology demonstrated that mTOR inhibition ameliorates spheroid pathology, revealing reversible mechanisms of axonal pathology.

active
experiment Created: 2026-04-27T23:26:20 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-c5035582258d
🧫 Experiment Protocol Cell BiologyAlzheimer's diseaseMTORipscextracted
iPSC-derived neurons with optical electrophysiology for functional studies
PRIMARY OUTCOME
Human iPSC-derived AD model with optical electrophysiology demonstrated that mTOR inhibition ameliorates spheroid pathology, revealing reversible mechanisms of axonal pathology.
Source: pmid_40065072
🧫 Experiment Extras
PATHWAY
PI3K/AKT/mTOR
MARKET PRICE
$0.50
STATUS
extracted
Related Target
MTORcomposite 0.419
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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