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Microglial depletion study using clodronate liposomes

experiment Created: 2026-04-10 22:34:11 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-169f2235-b61b-484a-889d-e
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Related Entities
Pde6b
Metadata
experiment_typecell_biology
protocolTreatment with clodronate-containing liposomes for microglial depletion, IGF-I treatment, TUNEL staining, comparison of cell death with and without microglia
expected_outcomesMicroglial depletion would affect IGF-I's neuroprotective capacity
success_criteriaChanges in IGF-I neuroprotective effect upon microglial depletion
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T15:34:11.650917
source_pmid22039242
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:34:11.957123'}
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Linked Artifacts (17)
related🧫In vivo IGF-I intravitreal injection in rd10 mice100%
related🧫Ex vivo IGF-I treatment in rd10 organotypic retinal explants100%
mentions📖PDE6B — Phosphodiesterase 6B80%
related📖PDE6B — Phosphodiesterase 6B72%
mentions📖IGF-1 Receptor Neurons70%
mentions📖IGF-1 Signaling Pathway in Neurodegeneration70%
related📖IGF-1 Receptor Neurons63%
related📖IGF-1 Signaling Pathway in Neurodegeneration63%
mentions📖Retinitis Pigmentosa60%
mentions📖Glial Cells60%
mentions📖Microglia60%
mentions📖Microglia60%
related📖Retinitis Pigmentosa60%
related📖Retinitis Pigmentosa54%
related📖Glial Cells54%
related📖Microglia54%
related📖Microglia54%