🧫
Ex vivo IGF-I treatment in rd10 organotypic retinal explants
active
experiment
Created: 2026-04-10T22:34:11
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-da891eb0-f020-4272-b989-5
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:34:11.654907'} |
| p_value | None |
| protocol | Organotypic retinal explants treated with IGF-I, cell death assessed by TUNEL staining and ELISA of free nucleosomes, microglial visualization by Cd11b and Iba1 immunolabeling, microglial depletion wi |
| effect_size | None |
| sample_size | None |
| source_pmid | 22039242 |
| extracted_at | 2026-04-10T15:34:11.650907 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Reduction in TUNEL-positive nuclei and free nucleosome levels |
| expected_outcomes | IGF-I treatment would reduce photoreceptor cell death and modulate microglial response |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
50%
Debates
0
Incoming
10
Outgoing
10
0 supporting
0 contradicting
0 neutral
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