🧫

MAPK pathway inhibition by QTJD through butyrate mechanism

experiment Created: 2026-04-10 22:50:13 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-31e47825-2119-4628-93a5-3
🧫 Experiment Protocol Cell Biology
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Related Entities
MAPK1, MAPK14, MAPK8, MAPK9
Metadata
experiment_typecell_biology
protocolWestern blotting analysis of ERK1/2, p38, and JNK1/2 phosphorylation following QTJD treatment
expected_outcomesQTJD inhibits MAPK pathway activation
success_criteriaSignificant reduction in MAPK protein phosphorylation
sample_sizeNone
statistical_methodsStatistical significance testing
p_value<0.01
effect_sizeNone
extracted_at2026-04-10T15:50:13.600164
source_pmid41754753
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:50:13.922211'}
🌍 Provenance Graph 1 nodes, 0 edges

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Linked Artifacts (50)
mentions📖MAPK1 Gene80%
mentions📖MAPK1 Protein (ERK2)80%
mentions📖mapk1-protein80%
mentions📖mapk1480%
mentions📖MAPK14 Protein80%
mentions📖mapk880%
mentions📖MAPK8 Protein (JNK1)80%
mentions📖MAPK9 Gene80%
mentions📖MAPK9 Protein (JNK2)80%
related📖MAPK1 Gene72%
related📖MAPK1 Protein (ERK2)72%
related📖mapk1-protein72%
related📖mapk1472%
related📖MAPK14 Protein72%
related📖mapk872%
related📖MAPK8 Protein (JNK1)72%
related📖MAPK9 Gene72%
related📖MAPK9 Protein (JNK2)72%
mentions📖erk170%
mentions📖ERK1 Protein70%
mentions📖ERK1 Protein70%
mentions📖ERK1 Protein70%
mentions📖JNK1 (MAPK8)70%
mentions📖JNK1 Protein70%
mentions📖MAPK Signaling Inhibitors: Investment Landscape Analysis70%
mentions📖MAPK/ERK Signaling Pathway in Neurodegeneration70%
mentions📖MAPK/ERK Signaling Pathway in Neurodegeneration70%
mentions📖MAPK/ERK and JAK-STAT Signaling in 4R-Tauopathies70%
mentions📖MAPK Signaling Pathways in Neurodegeneration70%
related📖erk163%
related📖ERK1 Protein63%
related📖ERK1 Protein63%
related📖ERK1 Protein63%
related📖JNK1 (MAPK8)63%
related📖JNK1 Protein63%
related📖MAPK Signaling Inhibitors: Investment Landscape Analysis63%
related📖MAPK/ERK Signaling Pathway in Neurodegeneration63%
related📖MAPK/ERK Signaling Pathway in Neurodegeneration63%
related📖MAPK/ERK and JAK-STAT Signaling in 4R-Tauopathies63%
related📖MAPK Signaling Pathways in Neurodegeneration63%
mentions📖experiments60%
related🧫GPR109A receptor validation using knockout macrophages57%
related📖experiments54%
mentions📖APP Gene Dosage Reduction Therapy for Down Syndrome50%
mentions📖Disease Rankings44%
mentions📖IRAK4 Kinase Modulation Therapy for Neurodegeneration44%
mentions📖GDNF Family Neurotrophic Factor Signaling Pathway in Neurode44%
mentions📖Mechanism Rankings44%
mentions📖Treatment Rankings44%
mentions📖JNK/p38 MAPK Signaling Pathway in Neurodegeneration44%