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CB2R deletion effects on GVHD-induced behavioral changes

experiment Created: 2026-04-11 00:45:12 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-3f48c883-7dc1-4f1d-92a8-0
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Metadata
experiment_typeanimal_model
protocolGVHD induction by irradiation followed by BM and splenocyte infusion from MHC-mismatched B10.BR donors into C57BL/6 recipients. Behavioral testing battery performed 14-18 days post-transplant includin
expected_outcomesExpected that CB2R deletion would protect against GVHD-induced behavioral dysregulation based on previous findings showing protection against neuroinflammation and neuronal loss
success_criteriaRescue of GVHD-induced behavioral abnormalities in CB2R knockout mice compared to wild-type mice
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T17:45:12.492724
source_pmid41958320
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-11T00:45:12.497887'}
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mentions📖Microglia60%
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