🧫

Rab27a knockdown effects on microglia activation in developing brain

experiment Created: 2026-04-10 23:11:59 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-94172f67-4aeb-44ba-a10e-5
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Related Entities
Rab27a
Metadata
experiment_typeanimal_model
protocolNeonatal electroporation, shRNA-mediated knockdown, immunofluorescence analysis of microglia
expected_outcomesIncreased rounded microglia following disruption of EV release
success_criteriaSignificant increase in CD11b/IBA1 positive rounded microglia
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T16:11:59.338877
source_pmid30816224
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T23:11:59.396328'}
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Linked Artifacts (40)
related🧪RAB27A-dependent extracellular vesicle engineering for mitoc100%
related📖RAB27A Gene100%
related📖RAB27A100%
mentions📖RAB27A Gene80%
mentions📖RAB27A Protein (Ras-Related Protein Rab-27A)80%
related📖RAB27A Protein (Ras-Related Protein Rab-27A)72%
mentions📖IBA1 Protein70%
related📖IBA1 Protein63%
mentions📖Astrocytes60%
mentions📖Astrocytes60%
mentions📖Microglia60%
mentions📖Microglia60%
mentions📖Subventricular Zone Neural Stem Cells60%
related🧪RAB27A-dependent extracellular vesicle engineering for mitoc60%
related🧪Microglia-Derived Extracellular Vesicle Engineering for Targ60%
related📖Astrocytes54%
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mentions📖Exosome Biogenesis in Neurodegeneration44%
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mentions📖Mitochondria-Lysosome Contact Sites (MLCS) in Neurodegenerat44%
mentions📖Mitochondria in Neurodegeneration44%
mentions📖mitochondrial-dynamics44%
mentions📖Mitochondrial Dynamics in Neurodegeneration44%
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mentions📖Section 244: Advanced Bioenergetics and ATP Restoration in C44%
related🧪Microglia-Derived Extracellular Vesicle Engineering for Targ33%
related🕸RAB27A co_discussed TFAM33%