🧫
High fiber diet effects on gut microbiome and neuroinflammation in aging
experiment
Created: 2026-04-10 23:12:36
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-981d6333-ef1b-486a-b6dd-1
🧫 Experiment Protocol
Animal Model
Metadata
| experiment_type | animal_model |
| protocol | 4-week dietary intervention with either 1% cellulose (low fiber) or 5% inulin (high fiber) diet, followed by gut microbiome analysis, SCFA measurement, histological assessment of colon inflammation, a |
| expected_outcomes | High fiber diet would increase beneficial gut bacteria, increase SCFA production, reduce intestinal inflammation, and promote anti-inflammatory microglial phenotype |
| success_criteria | Significant changes in gut microbiome composition, increased SCFA levels, reduced colonic inflammation scores, and altered microglial gene expression toward anti-inflammatory profile |
| sample_size | None |
| statistical_methods | None |
| p_value | None |
| effect_size | None |
| extracted_at | 2026-04-10T16:12:36.897393 |
| source_pmid | 30154787 |
| _origin | {'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T23:12:36.947913'} |
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