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Muscle-specific Tug knockout mice study

experiment Created: 2026-04-06 12:33:38 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-9f7727b4-4d76-4bcb-a541-9
🧫 Experiment Protocol Animal Model
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Related Entities
Tug (Aspscr1)
Metadata
experiment_typeanimal_model
protocolGeneration of muscle-specific knockout mice, metabolic phenotyping, glucose uptake assays, gene expression analysis
expected_outcomesReduced glucose uptake and altered energy expenditure due to loss of TUG cleavage pathway
success_criteriaMeasurable changes in glucose uptake and metabolic parameters
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-06T05:33:38.022647
source_pmid33686286
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:33:38.024843'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (3)
derives_from📄Insulin-stimulated endoproteolytic TUG cleavage links energy100%
related🧫TUG C-terminal product nuclear localization and PPARγ bindin100%
related🧫Muscle-specific constitutive TUG cleavage mice study100%

💬 Discussion