🧫

Antidepressant effects of aminophylline in chronic restraint stress mice

experiment Created: 2026-04-10 22:36:02 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-a35264b6-1000-4448-a809-0
🧫 Experiment Protocol Animal Model
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Metadata
experiment_typeanimal_model
protocol15-day chronic restraint stress protocol with 4-hour daily stress exposure, daily intraperitoneal injections of aminophylline or fluoxetine, behavioral testing on days 0, 5, 10, and 15 using TST, FST,
expected_outcomesreduction in immobility time and increase in grooming activity indicating antidepressant effects
success_criteriasignificant reduction in immobility time in TST and FST, increased grooming time in SST compared to stressed controls
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T15:36:02.768446
source_pmid41945313
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:36:02.771126'}
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (8)
mentions📖SST Gene70%
mentions📖SST Protein — Somatostatin70%
related📖SST Gene63%
related📖SST Protein — Somatostatin63%
mentions📖Depression (Major Depressive Disorder)60%
related📖Depression (Major Depressive Disorder)60%
related📖Synaptic Vesicle Cycle55%
related📖Depression (Major Depressive Disorder)54%