🧫
PPP3/calcineurin-dependent TFEB dephosphorylation mechanism
experiment
Created: 2026-04-06 12:28:58
By: experiment_extractor
Quality:
80%
✓ SciDEX
ID: experiment-exp-ad6850c9-f4ec-48ac-9df6-a
🧫 Experiment Protocol
Protein Interaction
Related Entities
Metadata
| experiment_type | protein_interaction |
| protocol | Calcium imaging, immunofluorescence microscopy, western blotting for phospho-TFEB, subcellular fractionation, phosphatase activity assays |
| expected_outcomes | Lysosomal calcium release would activate calcineurin, leading to TFEB dephosphorylation and nuclear translocation |
| success_criteria | Demonstration of calcium-dependent TFEB dephosphorylation and nuclear translocation that can be blocked by calcineurin inhibitors |
| sample_size | None |
| statistical_methods | None |
| p_value | None |
| effect_size | None |
| extracted_at | 2026-04-06T05:28:58.489681 |
| source_pmid | 30335591 |
| _origin | {'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:28:58.521361'} |
🌍 Provenance Graph
2 nodes, 1 edges
derives from (1)
Linked Artifacts (29)