🧫

Resveratrol effects on HK-2 cells under hypoxia/reoxygenation

active
experiment Created: 2026-04-11T00:45:03 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-b92b3e79-53a0-47b9-a559-6
🧫 Experiment Protocol Cell Biologyproposed
Related Entities
NFE2L2, HMOX1, TLR4, NFKB1
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:45:03.152331'}
p_valueNone
protocolHK-2 cell culture in high glucose medium, resveratrol pretreatment, hypoxia/reoxygenation induction, assessment of cell viability, oxidative stress, inflammatory markers, apoptosis, and protein expres
effect_sizeNone
sample_sizeNone
source_pmid41958068
extracted_at2026-04-10T17:45:03.101034
_schema_version1
experiment_typecell_biology
success_criteriaImproved cell survival, reduced oxidative stress and inflammation markers, decreased apoptosis, and consistent molecular pathway modulation matching animal model findings
expected_outcomesRSV treatment expected to improve cell viability, reduce oxidative damage and inflammatory responses, decrease apoptosis, and modulate Nrf2/HO-1 and TLR4/NF-κB signaling pathways similar to the animal
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
25
Outgoing
12
0 supporting 0 contradicting 0 neutral
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