🧫

Microglial activation by bEVs via Piezo1

experiment Created: 2026-04-10 22:33:25 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-e42ef64d-4f3c-4754-9ce7-6
🧫 Experiment Protocol Cell Biology
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Related Entities
Piezo1
Metadata
experiment_typecell_biology
protocolInvestigation of bEV effects on microglial Piezo1 both in vivo and in vitro
expected_outcomesbEVs activate microglial Piezo1 leading to microglial activation
success_criteriaDemonstration of Piezo1 activation and subsequent microglial response to bEV treatment
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T15:33:25.643706
source_pmid40731189
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:33:25.712839'}
Linked Artifacts (49)
related🧪Extracellular Matrix Stiffness Modulation100%
mentions📖PIEZO1 — Piezo Type Mechanosensitive Ion Channel Component 180%
related📖PIEZO1 — Piezo Type Mechanosensitive Ion Channel Component 172%
mentions📖Agitation in Alzheimer's Disease60%
mentions📖Alzheimer's Disease60%
mentions📖Alzheimer's Disease Genetic Variants60%
mentions📖Alzheimer's Disease vs Parkinson's Disease Compari60%
mentions📖APP Mutations in Alzheimer's Disease60%
mentions📖DLB, Parkinson's Disease, and Alzheimer's Disease:60%
mentions📖Early-Onset Alzheimer's Disease (EOAD)60%
mentions📖Investment Landscape: Alzheimer's Disease60%
mentions📖Preclinical Alzheimer's Disease60%
mentions📖Prodromal Alzheimer's Disease60%
mentions📖PSEN1 Mutations in Alzheimer's Disease60%
mentions📖PSEN2 Mutations in Alzheimer's Disease60%
mentions📖Sporadic vs Familial Alzheimer's Disease: Comprehensive60%
mentions📖TREM2 Variants in Alzheimer's Disease60%
mentions📖mechanisms60%
mentions📖Microglia60%
mentions📖Microglia60%
mentions📖neuroinflammation60%
related🧪Extracellular Matrix Stiffness Modulation60%
related📖Alzheimer's Disease60%
related📖Agitation in Alzheimer's Disease54%
related📖Alzheimer's Disease54%
related📖Alzheimer's Disease Genetic Variants54%
related📖Alzheimer's Disease vs Parkinson's Disease Compari54%
related📖APP Mutations in Alzheimer's Disease54%
related📖DLB, Parkinson's Disease, and Alzheimer's Disease:54%
related📖Early-Onset Alzheimer's Disease (EOAD)54%
related📖Investment Landscape: Alzheimer's Disease54%
related📖Preclinical Alzheimer's Disease54%
related📖Prodromal Alzheimer's Disease54%
related📖PSEN1 Mutations in Alzheimer's Disease54%
related📖PSEN2 Mutations in Alzheimer's Disease54%
related📖Sporadic vs Familial Alzheimer's Disease: Comprehensive54%
related📖TREM2 Variants in Alzheimer's Disease54%
related📖mechanisms54%
related📖Microglia54%
related📖Microglia54%
related📖neuroinflammation54%
mentions📖Sensory Neurons50%
mentions📖erk-mapk-signaling-neurodegeneration50%
mentions📖Efferocytosis in Neurodegeneration50%
mentions📖Mechanoreceptors44%
mentions📖Notch Signaling Modulation Therapy for Neurodegeneration44%
mentions📖Copper and Zinc Homeostasis in CBS/PSP44%
mentions📖Kinase and Phosphatase Therapeutic Target Matrix44%
mentions📖Section 180: Copper and Zinc Homeostasis in CBS/PSP44%