🧫
GWAS meta-analysis of major depressive disorder across three cohorts
active
experiment
Created: 2026-04-06T12:29:58
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-e84297de-2862-4904-be81-4
🧫 Experiment Protocol
Genetic Associationproposed
N = 336753
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:29:58.094530'} |
| p_value | 5e-08 |
| protocol | Meta-analysis of three GWAS datasets (23andMe, CONVERGE, PGC) followed by replication in GS:SFHS cohort. SNPs with P < 1×10^-7 in meta-analysis were selected for replication. Gene expression analysis |
| effect_size | None |
| sample_size | 336753 |
| source_pmid | 29728651 |
| extracted_at | 2026-04-06T05:29:58.092209 |
| _schema_version | 1 |
| experiment_type | genetic_association |
| success_criteria | P < 5×10^-8 for genome-wide significance in meta-analysis and replication |
| expected_outcomes | Discovery of novel genetic risk loci for MDD with genome-wide significance and validation in independent cohort |
| statistical_methods | Meta-analysis, genome-wide association testing, replication analysis |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
2
0 supporting
0 contradicting
0 neutral
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