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Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.
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📄 Paper Details
Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.
["Li X", "Luo Z", "Gu C", "Hall LS", "McIntosh AM", "Zeng Y", "Porteous DJ", "Hayward C", "Li M", "Yao YG", "Zhang C", "Luo XJ"]
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
PubMed
DOI
Abstract
Accumulating evidence suggests that genetic factors have a role in major depressive disorder (MDD). However, only limited MDD risk loci have been identified so far. Here we perform a meta-analysis (a total of 90,150 MDD cases and 246,603 controls) through combing three genome-wide association studies of MDD, including 23andMe (cases were self-reported with a clinical diagnosis or treatment of depression), CONVERGE (cases were diagnosed using the Composite International Diagnostic Interview) and ...
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
25%
Debates
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Incoming
5
Outgoing
0
0 supporting
0 contradicting
0 neutral
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