🧫

Autophagy receptor identification for stress granule elimination

experiment Created: 2026-04-04 05:25:10 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-f4dcbaa9-bddd-4c2c-80c3-a
🧫 Experiment Protocol Cell Biology
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Related Entities
SQSTM1, CALCOCO2
Metadata
experiment_typecell_biology
protocolautophagy receptor screening, protein interaction assays, stress granule localization studies, knockout experiments
expected_outcomesspecific autophagy receptors mediate stress granule elimination
success_criteriadirect interaction with G3BP1 and stress granule accumulation upon receptor knockout
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-04T05:25:03.816844
source_pmid36692217
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-04T05:25:10.899751'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (139)
derives_from📄Stress granule homeostasis is modulated by TRIM21-mediated u100%
experiment_target📖SQSTM1100%
mentions📖CALCOCO2100%
mentions📖SQSTM1100%
mentions📖SQSTM1 — Sequestosome 1 (p62)80%
mentions📖SQSTM1 Protein (p62/Sequestosome-1)80%
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mentions📖epidemiology-neurodegenerative-diseases80%
related📖SQSTM1 — Sequestosome 1 (p62)72%
related📖SQSTM1 Protein (p62/Sequestosome-1)72%
related📖SQSTM1/p62 Protein72%
mentions📖CALCOCO2 — Calcium Binding and Coiled-Coil Domain 270%
mentions📖G3BP170%
mentions📖G3BP1 Protein — Ras-GTPase-Activating Protein-Binding Protei70%
mentions📖NDP52 Gene70%
mentions📖NDP52 Protein70%
mentions📖SQSTM1/p6270%
related📖CALCOCO2 — Calcium Binding and Coiled-Coil Domain 263%
related📖G3BP163%
related📖G3BP1 Protein — Ras-GTPase-Activating Protein-Binding Protei63%
related📖NDP52 Gene63%
related📖NDP52 Protein63%
related📖SQSTM1/p6263%
mentions📖Calcium Dysregulation Across Neurodegenerative Diseases60%
mentions📖Lysosomal Enzyme Dysfunction Across Neurodegenerative Diseas60%
mentions📖Proteasome Dysfunction Across Neurodegenerative Diseases60%
mentions📖Autophagy60%
mentions📖mechanisms60%
mentions📖autophagy60%
related🧫Autophagy receptor knockout effects on stress granule accumu60%
related📖Calcium Dysregulation Across Neurodegenerative Diseases60%
related📖autophagy55%
related📖Calcium Dysregulation Across Neurodegenerative Diseases54%
related📖Lysosomal Enzyme Dysfunction Across Neurodegenerative Diseas54%
related📖Proteasome Dysfunction Across Neurodegenerative Diseases54%
related📖Autophagy54%
related📖mechanisms54%
related📖autophagy54%
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mentions📖Layer 4 Spiny Stellate Cells44%
mentions📖Prefrontal Cortex Pyramidal Neurons in Executive Function44%
mentions📖Spinal Lamina II Inner Neurons44%
mentions📖Synaptic Boutons44%
mentions📖TDP-43 Proteinopathy Neurons44%
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mentions📖VTA Dopamine Neurons in Schizophrenia44%
mentions📖autophagy-lysosomal-impairment-comparison44%
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mentions📖Alpha-Synuclein Clearance Mechanisms44%
mentions📖Alpha-Synuclein ESCRT-III Inhibition Mechanism44%
mentions📖Autophagic Cell Death Pathway in Neurodegeneration44%
mentions📖Autophagy Dysfunction in Progressive Supranuclear Palsy44%
mentions📖Autophagy-Lysosomal Impairment Comparison — AD/PD/ALS/FTD/HD44%
mentions📖Autophagy-Lysosomal Dysfunction in Neurodegenerative Disease44%
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mentions📖Autophagy Enhancers in Neurodegeneration44%
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