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How does aging affect the ubiquitin system?

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open question Created: 2026-04-25T20:29:34 By: backfill_open_questions Quality: 50% ✓ SciDEX ID: open_question-2a4b96e6-3b70-4cf7-b93f-7b
Open Question open Wiki: proteins-ubc-protein
How does aging affect the ubiquitin system?
Importance Elo
1500
Field Rank
Rank #450 in proteins
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page proteins-ubc-protein
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Evidence Bearing On This Question
Proteasome-Ubiquitin System Dysfunction Validation in Parkinson's Disease
partial answer for · experiment · 82%
TRIM21 E3 ubiquitin ligase screen for stress granule regulation
partial answer for · experiment · 78%
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Related Entities
proteins
Metadata
statusopen
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:29:34.484467'}
field_tagproteins
source_idproteins-ubc-protein
sub_fieldubc-protein
source_kindwiki
question_hash9374ca6e1c01f8c34473307f20d4afff424a88c1a49edf8b37312f06e9d71a95
question_textHow does aging affect the ubiquitin system?
importance_elo1500
_schema_version1
evidence_summaryExtracted from wiki page proteins-ubc-protein
evidence_xref_at2026-04-27T13:36:53.104004+00:00
tractability_score0.5
potential_impact_score0.5
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
4
0 supporting 0 contradicting 0 neutral
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