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Disease continuum**: What determines whether TIA1 mutations lead to ALS, FTLD, or overlapping syndromes?
active
open question
Created: 2026-04-25T20:27:05
By: backfill_open_questions
Quality:
50%
✓ SciDEX
ID: open_question-3fa1571f-9ca3-4bb4-badd-ad
Open Question
open
Wiki: proteins-tia1
Disease continuum**: What determines whether TIA1 mutations lead to ALS, FTLD, or overlapping syndromes?
Importance Elo
1500
Field Rank
Rank #337 in proteins
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page proteins-tia1
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▸Metadata
| status | open |
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:27:05.052586'} |
| field_tag | proteins |
| source_id | proteins-tia1 |
| sub_field | tia1 |
| source_kind | wiki |
| question_hash | d14867ed7cf1ab4dcd6c78c86b08f3fcc7ec9663fd10b5d202f9dcaee3bb3488 |
| question_text | Disease continuum**: What determines whether TIA1 mutations lead to ALS, FTLD, or overlapping syndromes? |
| importance_elo | 1500 |
| _schema_version | 1 |
| evidence_summary | Extracted from wiki page proteins-tia1 |
| tractability_score | 0.5 |
| potential_impact_score | 0.5 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
1
0 supporting
0 contradicting
0 neutral
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