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Intravenous immunoglobulins for Alzheimer's disease.
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ID: paper-25115546
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Intravenous immunoglobulins for Alzheimer's disease.
["Puli L", "Tanila H", "Relkin N"]
Abstract
Alzheimer's disease (AD) is a chronic neurodegenerative disease associated with intracerebral accumulation of aggregated amyloid-beta (Aβ) and tau proteins, as well as neuroinflammation. Human intravenous immunoglobulin (IVIG) is a mixture of polyclonal IgG antibodies isolated and pooled from thousands of healthy human donors. The scientific rationale for testing IVIG as a potential AD treatment include its natural anti-Aβ antibody activity, its favorable safety profile and inherent anti-inflamm...
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