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Cell signaling stabilizes morphogenesis against noise.
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ID: paper-31628213
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Cell signaling stabilizes morphogenesis against noise.
["Hagolani P", "Zimm R", "Marin-Riera M", "Salazar-Ciudad I"]
Abstract
Embryonic development involves gene networks, extracellular signaling, cell behaviors (cell division, adhesion, etc.) and mechanical interactions. How should these be coordinated to lead to complex and robust morphologies? To explore this question, we randomly wired genes and cell behaviors into a huge number of networks in EmbryoMaker. EmbryoMaker is a computational model of animal development that simulates how the 3D positions of cells, i.e. morphology, change over time due to such networks. ...
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