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Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility.
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ID: paper-33298875
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Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility.
["Wang F", "Huang S", "Gao R", "Zhou Y", "Lai C", "Li Z", "Xian W", "Qian X", "Li Z", "Huang Y"]
Abstract
The COVID-19 pandemic has accounted for millions of infections and hundreds of thousand deaths worldwide in a short-time period. The patients demonstrate a great diversity in clinical and laboratory manifestations and disease severity. Nonetheless, little is known about the host genetic contribution to the observed interindividual phenotypic variability. Here, we report the first host genetic study in the Chinese population by deeply sequencing and analyzing 332 COVID-19 patients categorized by ...
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