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Fig. 7: Effect of proinflammatory cytokines on brain microvascular endothelial barrier f...
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Created: 2026-04-16T11:31:39
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ID: paper-fig-37245027-7
Fig. 7Figure 7
Effect of proinflammatory cytokines on brain microvascular endothelial barrier function. a TER measurements across confluent monolayers of mouse brain microvascular endothelial cells treated with IL-1β (2–200 ng/mL) and IL-1β + TNF-α (20 ng/mL each). The data were represented as resistance change. Mean ± S.E.M., n = 3. Arrow indicates when cytokines were added. b Summary data showing TER changes in brain microvascular endothelial cells treated with IL-1β and IL-1β + TNF-α. Kruskal–Wallis test with Dunn’s multiple comparisons test, P < 0.0001, IL-1β (2–200 ng/mL) vs. control (vehicle) group; P < 0.0001, IL-1β + TNF-α (20 ng/mL each) vs. control (vehicle). c Immunocytochemical analysis of claudin-5, VE-cadherin and ZO-1 (red) on brain microvascular endothelial cells under control conditions (vehicle) and after IL-1β (20 ng/mL) treatment in vitro. Nuclei was stained with DAPI. White arrows indicate TJ disorganization
▸Metadata
| doi | |
| pmcid | PMC10223932 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC10223932/bin/12974_2023_2817_Fig7_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-16T11:31:39.746599'} |
| caption | Effect of proinflammatory cytokines on brain microvascular endothelial barrier function. a TER measurements across confluent monolayers of mouse brain microvascular endothelial cells treated with IL |
| paper_id | 37245027 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC10223932/bin/12974_2023_2817_Fig7_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 7 |
| figure_number | 7 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
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