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FIGURE 5 — Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophys
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Created: 2026-04-21T18:29:40
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ID: paper-fig-paper-eba56eb9e84f-5
FIGURE 5Figure 5
Frataxin silencing causes SR Ca 2+ store depletion in cardiomyocytes. (A) Loading of Fura2-AM. (B,D,F) FxnKD cells show a marked difference to 1 μM thapsigargin response compared to Scr. (C–G) The amplitude of the response in relative values % shows a significant decrease in FxnKD cells which reveals a decrease of Ca 2+ content in the SR ( ∗ p < 0.05; ∗∗ p < 0.005). Scale bar (20 mm).
▸Metadata
| pmid | paper-eba56eb9e84f |
| caption | Frataxin silencing causes SR Ca 2+ store depletion in cardiomyocytes. (A) Loading of Fura2-AM. (B,D,F) FxnKD cells show a marked difference to 1 μM thapsigargin response compared to Scr. (C–G) |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC6176067/bin/fncel-12-00264-g005.jpg |
| paper_title | Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology. |
| figure_label | FIGURE 5 |
| figure_number | 5 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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