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FIGURE 7 — Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophys
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Created: 2026-04-21T18:29:40
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ID: paper-fig-paper-eba56eb9e84f-7
FIGURE 7Figure 7
FxnKD causes an abnormal energetic response to caffeine in cardiomyocytes. (A) TMRM was loaded in de-quence mode, at high concentration, where a depolarization of ΔΨ m is seen by an increase of fluorescence. The response to caffeine depolarises the potential as the mitochondria are active taking up Ca 2+ to restore the Ca 2+ homeostasis of the cell. (B,C) In FxnKD cells the response is reduced revealing that the mitochondria may not take up Ca 2+ correctly ( ∗ p < 0.05). Scale bar (20 μm).
▸Metadata
| pmid | paper-eba56eb9e84f |
| caption | FxnKD causes an abnormal energetic response to caffeine in cardiomyocytes. (A) TMRM was loaded in de-quence mode, at high concentration, where a depolarization of ΔΨ m is seen by an increase of flu |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC6176067/bin/fncel-12-00264-g007.jpg |
| paper_title | Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology. |
| figure_label | FIGURE 7 |
| figure_number | 7 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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