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Rigor Score Card: Dominant-Negative Spliceosome Titration

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rigor score card Created: 2026-04-27T01:15:27 By: rigor_score_card Quality: 22% ✓ SciDEX ID: rsc-h-SDA-2026-04-26-gap-6734250e
⚖️ Rigor Score Card
Scoring: Dominant-Negative Spliceosome Titration
DimensionminimaxglmReconciled
Scientific Premise12?
Study Design11?
Blinding11?
Power Analysis11?
Resource Identification11?
Statistical Reporting11?
Data Availability11?
Sabv11?
Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong
Metadata
dimensions['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw{'scores': {'sabv': {'score': 1, 'evidence': 'Dominant-Negative Spliceosome Titration', 'location': 'no mention of sex considerations or disaggregated analysis'}, 'blinding': {'score': 1, 'evidence':
eval_b_raw{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable, no disaggregation by sex, no consideration of sex-specific effects on the GBA mechanism.', 'location': 'Overal
provider_aminimax
provider_bglm
reconciled{'reconciler_notes': 'High inter-rater agreement observed across all 8 dimensions. For scientific_premise, Evaluator A gave a score of 1 while Evaluator B gave a 2 (difference = 1, within threshold);
_schema_version1
scored_entity_idh-SDA-2026-04-26-gap-pubmed-20260412-094853-199f4f1b-01-dominant-negative-spliceosome-titration-20b316433d
scored_entity_typehypothesis
scored_entity_titleDominant-Negative Spliceosome Titration
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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